Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'MAP kinase-activated protein kinase 2 [41-364]' and Ligand = 'BDBM30305'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 [41-364] (Homo sapiens (Human))	BDBM30305 (indole-based 7-membered lactam, 25f) Show SMILES CNCC1CNC(=O)c2cc3ccc(cc3n2C1)C(=O)Nc1nccs1 Show InChI InChI=1S/C18H19N5O2S/c1-19-8-11-9-21-17(25)15-6-12-2-3-13(7-14(12)23(15)10-11)16(24)22-18-20-4-5-26-18/h2-7,11,19H,8-10H2,1H3,(H,21,25)(H,20,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...				Bioorg Med Chem Lett 18: 1994-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.119 BindingDB Entry DOI: 10.7270/Q2ZW1J8V
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