Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'MAP kinase-interacting serine/threonine-protein kinase 2' and Ligand = 'BDBM164600'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM164600 (US9669031, 21 N-[6-[(1,5-dioxospiro[2H-imidazo[1,5...) Show SMILES O=C(Nc1cc(Nc2ccc3C(=O)NC4(CCCC4)n3c2=O)ncn1)C1CC1 Show InChI InChI=1S/C19H20N6O3/c26-16(11-3-4-11)23-15-9-14(20-10-21-15)22-12-5-6-13-17(27)24-19(7-1-2-8-19)25(13)18(12)28/h5-6,9-11H,1-4,7-8H2,(H,24,27)(H2,20,21,22,23,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	25
eFFECTOR THERAPEUTICS, INC. US Patent					Assay Description Compounds are screened for Mnk inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...				US Patent US9669031 (2017) BindingDB Entry DOI: 10.7270/Q26Q1VDT
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