BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'MAP kinase-interacting serine/threonine-protein kinase 2' and Ligand = 'BDBM50455558'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
MAP kinase-interacting serine/threonine-protein kinase 2


(Homo sapiens (Human))		BDBM50455558
PNG
(CHEMBL4213023)
Show SMILES Oc1ccc(cc1)-c1cnc2cnc(cn12)-c1ccccc1
Show InChI InChI=1S/C18H13N3O/c22-15-8-6-14(7-9-15)17-10-20-18-11-19-16(12-21(17)18)13-4-2-1-3-5-13/h1-12,22H
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 415n/an/an/an/an/an/a



Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged MNK2 (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...

J Med Chem 61: 4348-4369 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01714
BindingDB Entry DOI: 10.7270/Q20004P7
More data for this
Ligand-Target Pair