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Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM238227'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Mus musculus (Mouse))
BDBM238227
PNG
(US9403804, 4)
Show SMILES CC1(C)CCC(=CC1)c1cc(ccc1NC(=O)c1nc(c[nH]1)C#N)C1(CC1)C#N |c:5|
Show InChI InChI=1S/C23H23N5O/c1-22(2)7-5-15(6-8-22)18-11-16(23(14-25)9-10-23)3-4-19(18)28-21(29)20-26-13-17(12-24)27-20/h3-5,11,13H,6-10H2,1-2H3,(H,26,27)(H,28,29)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 9.5n/an/an/an/a7.525



Janssen Pharmaceutica NV

US Patent


Assay Description
An autophosphorylation, fluorescence polarization competition immunoassay was used to determine the potency for c-fms inhibition exhibited by selecte...


US Patent US9403804 (2016)


BindingDB Entry DOI: 10.7270/Q23T9G3C
More data for this
Ligand-Target Pair