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Found 1 hit Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM27898'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM27898
PNG
(2-(benzylamino)-8-(2,3-dihydro-1H-inden-5-yl)-N-me...)
Show SMILES CONC(=O)c1cn(-c2ccc3CCCc3c2)c2nc(NCc3ccccc3)ncc2c1=O
Show InChI InChI=1S/C25H23N5O3/c1-33-29-24(32)21-15-30(19-11-10-17-8-5-9-18(17)12-19)23-20(22(21)31)14-27-25(28-23)26-13-16-6-3-2-4-7-16/h2-4,6-7,10-12,14-15H,5,8-9,13H2,1H3,(H,29,32)(H,26,27,28)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 75n/an/an/an/a7.522



Johnson & Johnson Pharmaceutical



Assay Description
FMS was assayed using a fluorescence polarization (FP) competition immunoassay that measured FMS phosphorylation of FMS 555-568 peptide at Y561. The ...


J Med Chem 52: 1081-99 (2009)


Article DOI: 10.1021/jm801406h
BindingDB Entry DOI: 10.7270/Q21834T7
More data for this
Ligand-Target Pair