Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM50560793 (CHEMBL4788945) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human His-tagged CSF1R (538 to 910 residues) preincubated for 20 mins followed by ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00936 BindingDB Entry DOI: 10.7270/Q2Q81HSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage colony-stimulating factor 1 receptor (Mus musculus (Mouse)) | BDBM50560793 (CHEMBL4788945) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 228 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of CSF1R in mouse NFS-60 cells assessed as reduction in CSF-induced cell proliferation after 72 hrs by CellTiter-Glo assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00936 BindingDB Entry DOI: 10.7270/Q2Q81HSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM50560793 (CHEMBL4788945) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to human wild type CSF1R (I564 to S939 residues) expressed in bacterial expression system by kinome scan assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00936 BindingDB Entry DOI: 10.7270/Q2Q81HSS | |||||||||||
More data for this Ligand-Target Pair |