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Found 1 hit Enz. Inhib. hit(s) with Target = 'Malignant T-cell-amplified sequence 1' and Ligand = 'BDBM403118'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Malignant T-cell-amplified sequence 1


(Homo sapiens (human))		BDBM403118
PNG
(US10329303, Example 14)
Show SMILES CC(C)Cn1c2sc(Cc3c(C)n[nH]c3C)c(-c3cccc(c3)C(O)C(F)(F)F)c2c(=O)n(C)c1=O
Show InChI InChI=1S/C25H27F3N4O3S/c1-12(2)11-32-23-20(22(34)31(5)24(32)35)19(18(36-23)10-17-13(3)29-30-14(17)4)15-7-6-8-16(9-15)21(33)25(26,27)28/h6-9,12,21,33H,10-11H2,1-5H3,(H,29,30)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<20n/an/an/an/a



Virginia Commonwealth University



Assay Description
pecific Examples 1-52 of compounds of the invention, with estimated EC50 values determined using an MTT assay for 4-day viability of Raji (Burkitt...

Bioorg Med Chem 17: 6496-504 (2009)


BindingDB Entry DOI: 10.7270/Q2B27XM9
More data for this
Ligand-Target Pair