Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit [D816V]' and Ligand = 'BDBM369256'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit [D816V] (Homo sapiens (Human))	BDBM369256 (N-[4-[6-[1-(cyclopropanecarbonyl)-3,6- dihydro-2H-...) Show SMILES Fc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-c1ncnc2cc(sc12)C1=CCN(CC1)C(=O)C1CC1 |t:30| Show InChI InChI=1S/C27H23FN4O3S2/c28-20-5-9-22(10-6-20)37(34,35)31-21-7-3-18(4-8-21)25-26-23(29-16-30-25)15-24(36-26)17-11-13-32(14-12-17)27(33)19-1-2-19/h3-11,15-16,19,31H,1-2,12-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universitàadi Roma					Assay Description The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...				J Med Chem 51: 1560-76 (2008) BindingDB Entry DOI: 10.7270/Q2HX1FZW
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