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Found 1 hit Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit [D816V]' and Ligand = 'BDBM397924'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mast/stem cell growth factor receptor Kit [D816V]


(Homo sapiens (Human))		BDBM397924
PNG
(US9994552, Compound 135)
Show SMILES CCOc1cc2ncnc(N3CCN(CC3)c3ncc(Cc4ccccc4)c(N)n3)c2cc1OCC1CCN(C)CC1
Show InChI InChI=1S/C32H40N8O2/c1-3-41-29-19-27-26(18-28(29)42-21-24-9-11-38(2)12-10-24)31(36-22-35-27)39-13-15-40(16-14-39)32-34-20-25(30(33)37-32)17-23-7-5-4-6-8-23/h4-8,18-20,22,24H,3,9-17,21H2,1-2H3,(H2,33,34,37)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a<1n/an/an/an/an/an/a



Duquesne University



Assay Description
Kit D816V assay: In each well of a 384-well plate, 0.04 ng/ul (0.5 nM) of D816V Kit (Carna Bioscience 08-156) was incubated in a total of 12.5 ul of ...

J Med Chem 52: 4892-902 (2009)


BindingDB Entry DOI: 10.7270/Q27M0B8Q
More data for this
Ligand-Target Pair