Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Maternal embryonic leucine zipper kinase' and Ligand = 'BDBM166122'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM166122 (US9067937, 66) Show SMILES CC(=O)c1cnc2ccc(nc2c1N[C@H]1CC[C@H](N)CC1)-c1cc(Cl)c(O)c(Cl)c1 |r,wU:14.15,wD:17.19,(6.67,-1.71,;5.33,-.94,;5.33,.6,;4,-1.71,;4,-3.25,;2.67,-4.02,;1.33,-3.25,;,-4.02,;-1.33,-3.25,;-1.33,-1.71,;,-.94,;1.33,-1.71,;2.67,-.94,;2.67,.94,;1.33,1.71,;,.94,;-1.33,1.71,;-1.33,3.25,;-2.67,4.02,;,4.02,;1.33,3.25,;-2.67,-.94,;-2.67,.6,;-4,1.37,;-4,2.91,;-5.33,.6,;-6.67,1.37,;-5.33,-.94,;-6.67,-1.71,;-4,-1.71,)| Show InChI InChI=1S/C22H22Cl2N4O2/c1-11(29)15-10-26-19-7-6-18(12-8-16(23)22(30)17(24)9-12)28-21(19)20(15)27-14-4-2-13(25)3-5-14/h6-10,13-14,30H,2-5,25H2,1H3,(H,26,27)/t13-,14-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	7.4	25
OncoTherapy Science, Inc. US Patent					Assay Description MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...				US Patent US9067937 (2015) BindingDB Entry DOI: 10.7270/Q2BR8QX4
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