BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Matrix metalloproteinase-14' and Ligand = 'BDBM429758'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Matrix metalloproteinase-14


(Homo sapiens (Human))		BDBM429758
PNG
((5R)-5-[3-[4- (4-chloro-2- methoxy- phenyl)-1- pip...)
Show SMILES COc1cc(Cl)ccc1C1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O |r|
Show InChI InChI=1S/C19H24ClN3O4/c1-19(17(25)21-18(26)22-19)8-5-16(24)23-9-6-12(7-10-23)14-4-3-13(20)11-15(14)27-2/h3-4,11-12H,5-10H2,1-2H3,(H2,21,22,25,26)/t19-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>100n/an/an/an/an/an/a



GALAPAGOS NV

US Patent


Assay Description
The basis for the assay is the cleavage of the substrate 390 MMP FRET Substrate I (Anaspec Cat# AS-27076) by human MMP14 (Biomol, Cat#SE-259).For the...

US Patent US10550100 (2020)


BindingDB Entry DOI: 10.7270/Q2D2211N
More data for this
Ligand-Target Pair