BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Matrix metalloproteinase-14' and Ligand = 'BDBM50450405'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Matrix metalloproteinase-14


(Homo sapiens (Human))		BDBM50450405
PNG
(CHEMBL4167912)
Show SMILES CNC(=O)[C@@H](NC(=O)c1ccc(o1)-c1ccc(CCc2nc3CCCc3c(=O)[nH]2)c(F)c1)C(C)C |r|
Show InChI InChI=1S/C26H29FN4O4/c1-14(2)23(26(34)28-3)31-25(33)21-11-10-20(35-21)16-8-7-15(18(27)13-16)9-12-22-29-19-6-4-5-17(19)24(32)30-22/h7-8,10-11,13-14,23H,4-6,9,12H2,1-3H3,(H,28,34)(H,31,33)(H,29,30,32)/t23-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Graz University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human MMP14 expressed in Escherichia coli using fTHP-15 as substrate preincubated for 30 mins followed by substrate additio...

Bioorg Med Chem 26: 4984-4995 (2018)


Article DOI: 10.1016/j.bmc.2018.08.020
BindingDB Entry DOI: 10.7270/Q25141SR
More data for this
Ligand-Target Pair