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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 1' and Ligand = 'BDBM50120677'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor 1


(RAT)
BDBM50120677
PNG
(CHEMBL3618341)
Show SMILES COc1cc(ccc1OCC(O)C1CC1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cn1
Show InChI InChI=1S/C23H21ClN4O4/c1-31-22-9-17(5-7-21(22)32-12-20(29)14-2-3-14)27-13-26-28-11-15(8-19(28)23(27)30)18-6-4-16(24)10-25-18/h4-11,13-14,20,29H,2-3,12H2,1H3
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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
12n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Displacement of [125I][Phe13,Tyr19]-MCH from rat MCHR1 by scintillation counting analysis


Bioorg Med Chem Lett 25: 4412-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.09.018
BindingDB Entry DOI: 10.7270/Q2JD4ZMW
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))
BDBM50120677
PNG
(CHEMBL3618341)
Show SMILES COc1cc(ccc1OCC(O)C1CC1)-n1cnn2cc(cc2c1=O)-c1ccc(Cl)cn1
Show InChI InChI=1S/C23H21ClN4O4/c1-31-22-9-17(5-7-21(22)32-12-20(29)14-2-3-14)27-13-26-28-11-15(8-19(28)23(27)30)18-6-4-16(24)10-25-18/h4-11,13-14,20,29H,2-3,12H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
13n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Displacement of [125I][Phe13,Tyr19]-MCH from human MCHR1 expressed in HEK293 cells by scintillation counting analysis


Bioorg Med Chem Lett 25: 4412-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.09.018
BindingDB Entry DOI: 10.7270/Q2JD4ZMW
More data for this
Ligand-Target Pair