Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 1' and Ligand = 'BDBM50153203'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153203 (CHEMBL187854 | N-(2-Diethylamino-ethyl)-2-methoxy-...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(cc2)C(F)(F)F)cc1OC Show InChI InChI=1S/C22H27F3N4O3/c1-4-29(5-2)13-12-26-20(30)18-11-10-17(14-19(18)32-3)28-21(31)27-16-8-6-15(7-9-16)22(23,24)25/h6-11,14H,4-5,12-13H2,1-3H3,(H,26,30)(H2,27,28,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153203 (CHEMBL187854 | N-(2-Diethylamino-ethyl)-2-methoxy-...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(cc2)C(F)(F)F)cc1OC Show InChI InChI=1S/C22H27F3N4O3/c1-4-29(5-2)13-12-26-20(30)18-11-10-17(14-19(18)32-3)28-21(31)27-16-8-6-15(7-9-16)22(23,24)25/h6-11,14H,4-5,12-13H2,1-3H3,(H,26,30)(H2,27,28,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using scintillation proximity ass...				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50153203 (CHEMBL187854 | N-(2-Diethylamino-ethyl)-2-methoxy-...) Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(cc2)C(F)(F)F)cc1OC Show InChI InChI=1S/C22H27F3N4O3/c1-4-29(5-2)13-12-26-20(30)18-11-10-17(14-19(18)32-3)28-21(31)27-16-8-6-15(7-9-16)22(23,24)25/h6-11,14H,4-5,12-13H2,1-3H3,(H,26,30)(H2,27,28,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assay				Bioorg Med Chem Lett 14: 5075-80 (2004) Article DOI: 10.1016/j.bmcl.2004.07.077 BindingDB Entry DOI: 10.7270/Q2CF9PKT
					More data for this Ligand-Target Pair