Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 1' and Ligand = 'BDBM50381385'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381385 (CHEMBL2016779) Show SMILES CCC1(O)CCN(CC1)c1nc(C)c2cc(NC(=O)COc3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C25H27F3N4O4/c1-3-24(34)10-12-32(13-11-24)23-29-16(2)20-14-17(4-9-21(20)31-23)30-22(33)15-35-18-5-7-19(8-6-18)36-25(26,27)28/h4-9,14,34H,3,10-13,15H2,1-2H3,(H,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH peptide mediated response measuring [3H]inositol phosphate...				Bioorg Med Chem Lett 22: 3157-62 (2012) Article DOI: 10.1016/j.bmcl.2012.03.050 BindingDB Entry DOI: 10.7270/Q2D79CFJ
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381385 (CHEMBL2016779) Show SMILES CCC1(O)CCN(CC1)c1nc(C)c2cc(NC(=O)COc3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C25H27F3N4O4/c1-3-24(34)10-12-32(13-11-24)23-29-16(2)20-14-17(4-9-21(20)31-23)30-22(33)15-35-18-5-7-19(8-6-18)36-25(26,27)28/h4-9,14,34H,3,10-13,15H2,1-2H3,(H,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by SPA binding assay				Bioorg Med Chem Lett 22: 3157-62 (2012) Article DOI: 10.1016/j.bmcl.2012.03.050 BindingDB Entry DOI: 10.7270/Q2D79CFJ
					More data for this Ligand-Target Pair