Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 1 [E4Q,A5T]' and Ligand = 'BDBM258666'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 [E4Q,A5T] (Homo sapiens (Human))	BDBM258666 (US9499482, 65) Show SMILES Cc1cc(ccc1OCCN1CCC1)N1CC[C@H](Oc2ccc(cc2)C2CC2)C1=O |r| Show InChI InChI=1S/C25H30N2O3/c1-18-17-21(7-10-23(18)29-16-15-26-12-2-13-26)27-14-11-24(25(27)28)30-22-8-5-20(6-9-22)19-3-4-19/h5-10,17,19,24H,2-4,11-16H2,1H3/t24-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.800	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Company US Patent					Assay Description An in vitro binding assay was used to determine the compound Ki value or ability to antagonize binding of a peptide agonist to the human melanin conc...				US Patent US9499482 (2016) BindingDB Entry DOI: 10.7270/Q2M907KT
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