Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 1 [E4Q,A5T]' and Ligand = 'BDBM258749'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 [E4Q,A5T] (Homo sapiens (Human))	BDBM258749 (US9499482, 148) Show SMILES COc1cc(ccc1OCCN(C)CCO)N1CC=C(Oc2ccc(cc2)C2CC2)C1=O |t:19| Show InChI InChI=1S/C25H30N2O5/c1-26(13-15-28)14-16-31-22-10-7-20(17-24(22)30-2)27-12-11-23(25(27)29)32-21-8-5-19(6-9-21)18-3-4-18/h5-11,17-18,28H,3-4,12-16H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.800	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Company US Patent					Assay Description An in vitro binding assay was used to determine the compound Ki value or ability to antagonize binding of a peptide agonist to the human melanin conc...				US Patent US9499482 (2016) BindingDB Entry DOI: 10.7270/Q2M907KT
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