Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 1 [E4Q,A5T]' and Ligand = 'BDBM258758'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 [E4Q,A5T] (Homo sapiens (Human))	BDBM258758 (US9499482, 157) Show SMILES COc1cc(ccc1OCCN1CC(O)(C1)C1CC1)N1CCC(Oc2ccc(cc2)C2CC2)C1=O Show InChI InChI=1S/C28H34N2O5/c1-33-26-16-22(8-11-24(26)34-15-14-29-17-28(32,18-29)21-6-7-21)30-13-12-25(27(30)31)35-23-9-4-20(5-10-23)19-2-3-19/h4-5,8-11,16,19,21,25,32H,2-3,6-7,12-15,17-18H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Company US Patent					Assay Description An in vitro binding assay was used to determine the compound Ki value or ability to antagonize binding of a peptide agonist to the human melanin conc...				US Patent US9499482 (2016) BindingDB Entry DOI: 10.7270/Q2M907KT
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