Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 1 [E4Q,A5T]' and Ligand = 'BDBM258786'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 [E4Q,A5T] (Homo sapiens (Human))	BDBM258786 (US9499482, 193) Show SMILES CC1(O)CN(CCOc2ccc(cc2Br)N2CC=C(Oc3ccc(cc3)C3CC3)C2=O)C1 |t:18| Show InChI InChI=1S/C25H27BrN2O4/c1-25(30)15-27(16-25)12-13-31-22-9-6-19(14-21(22)26)28-11-10-23(24(28)29)32-20-7-4-18(5-8-20)17-2-3-17/h4-10,14,17,30H,2-3,11-13,15-16H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.600	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Company US Patent					Assay Description An in vitro binding assay was used to determine the compound Ki value or ability to antagonize binding of a peptide agonist to the human melanin conc...				US Patent US9499482 (2016) BindingDB Entry DOI: 10.7270/Q2M907KT
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