Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 3' and Ligand = 'BDBM50266731'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 3 (Mus musculus)	BDBM50266731 (CHEMBL4092424) Show SMILES CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](Cc1csc2ccccc12)C(N)=O |r| Show InChI InChI=1S/C37H43IN8O5S/c1-22(47)43-30(18-23-8-3-2-4-9-23)35(50)44-28(11-7-17-42-37(40)41)34(49)46-31(19-24-13-15-26(38)16-14-24)36(51)45-29(33(39)48)20-25-21-52-32-12-6-5-10-27(25)32/h2-6,8-10,12-16,21,28-31H,7,11,17-20H2,1H3,(H2,39,48)(H,43,47)(H,44,50)(H,45,51)(H,46,49)(H4,40,41,42)/t28-,29-,30-,31+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Displacement of [125I]-NDP-MSH from mouse MC3R expressed in HEK293 cells after 1 hr by gamma counting				J Med Chem 60: 4342-4357 (2017) Article DOI: 10.1021/acs.jmedchem.7b00301 BindingDB Entry DOI: 10.7270/Q24170J1
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Mus musculus)	BDBM50266731 (CHEMBL4092424) Show SMILES CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@@H](Cc1csc2ccccc12)C(N)=O |r| Show InChI InChI=1S/C37H43IN8O5S/c1-22(47)43-30(18-23-8-3-2-4-9-23)35(50)44-28(11-7-17-42-37(40)41)34(49)46-31(19-24-13-15-26(38)16-14-24)36(51)45-29(33(39)48)20-25-21-52-32-12-6-5-10-27(25)32/h2-6,8-10,12-16,21,28-31H,7,11,17-20H2,1H3,(H2,39,48)(H,43,47)(H,44,50)(H,45,51)(H,46,49)(H4,40,41,42)/t28-,29-,30-,31+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	930	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at mouse MC3R expressed in HEK293 cells assessed as induction of cAMP accumulation after 2 hrs by alpha screen assay				J Med Chem 60: 4342-4357 (2017) Article DOI: 10.1021/acs.jmedchem.7b00301 BindingDB Entry DOI: 10.7270/Q24170J1
					More data for this Ligand-Target Pair