Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50134495 (1'-[3-(4-chlorophenyl)-2-[(3R)-1,2-dihydro-3-isoqu...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibitory activity against [125I]-NDP-alpha-MSH binding to the human melanocortin 4 receptor | Bioorg Med Chem Lett 14: 377-81 (2003) BindingDB Entry DOI: 10.7270/Q2902363 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50134495 (1'-[3-(4-chlorophenyl)-2-[(3R)-1,2-dihydro-3-isoqu...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Intracellular level of cAMP in cells expressing the melanocortin 4 receptor | Bioorg Med Chem Lett 14: 377-81 (2003) BindingDB Entry DOI: 10.7270/Q2902363 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50134495 (1'-[3-(4-chlorophenyl)-2-[(3R)-1,2-dihydro-3-isoqu...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 190 | n/a | n/a | n/a | n/a |
Neurocrine Biosciences Inc. Curated by ChEMBL | Assay Description Agonistic activity measured as inhibition of cAMP accumulation in HEK cells expressing human Melanocortin 4 receptor (hMC4R) | Bioorg Med Chem Lett 13: 3793-6 (2003) BindingDB Entry DOI: 10.7270/Q2P26ZNW | |||||||||||
More data for this Ligand-Target Pair |