Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50136355'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50136355 (3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-(4-cyclohexyl...) Show SMILES NCCC(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C26H37ClN6O2/c27-22-8-6-20(7-9-22)16-23(31-24(34)10-13-28)25(35)32-14-11-26(12-15-32,17-33-19-29-18-30-33)21-4-2-1-3-5-21/h6-9,18-19,21,23H,1-5,10-17,28H2,(H,31,34)/t23-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Stimulation of adenylate cyclase in HEK293 cells expressing the human MC4R receptor was determined by measuring cAMP accumulation using the RPA559 SP...				Bioorg Med Chem Lett 13: 4341-4 (2003) BindingDB Entry DOI: 10.7270/Q2F18Z4D
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50136355 (3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-(4-cyclohexyl...) Show SMILES NCCC(=O)N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(CC1)C1CCCCC1 Show InChI InChI=1S/C26H37ClN6O2/c27-22-8-6-20(7-9-22)16-23(31-24(34)10-13-28)25(35)32-14-11-26(12-15-32,17-33-19-29-18-30-33)21-4-2-1-3-5-21/h6-9,18-19,21,23H,1-5,10-17,28H2,(H,31,34)/t23-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Stimulation of adenylate cyclase in HEK293 cells expressing the human MC4R receptor was determined by measuring cAMP accumulation using the RPA559 SP...				Bioorg Med Chem Lett 13: 4341-4 (2003) BindingDB Entry DOI: 10.7270/Q2F18Z4D
					More data for this Ligand-Target Pair