Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50191011'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50191011 ((R)-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-(trifluo...) Show SMILES CC(C)C[C@H](N)c1cc(ccc1N1CCN(CC1)C(=O)[C@H](C)Cc1ccc(Cl)cc1Cl)C(F)(F)F Show InChI InChI=1S/C26H32Cl2F3N3O/c1-16(2)12-23(32)21-14-19(26(29,30)31)5-7-24(21)33-8-10-34(11-9-33)25(35)17(3)13-18-4-6-20(27)15-22(18)28/h4-7,14-17,23H,8-13,32H2,1-3H3/t17-,23+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from human MC4R stably expressed in HEK293 cells				Bioorg Med Chem Lett 16: 4800-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.075 BindingDB Entry DOI: 10.7270/Q2NC60VS
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50191011 ((R)-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-(trifluo...) Show SMILES CC(C)C[C@H](N)c1cc(ccc1N1CCN(CC1)C(=O)[C@H](C)Cc1ccc(Cl)cc1Cl)C(F)(F)F Show InChI InChI=1S/C26H32Cl2F3N3O/c1-16(2)12-23(32)21-14-19(26(29,30)31)5-7-24(21)33-8-10-34(11-9-33)25(35)17(3)13-18-4-6-20(27)15-22(18)28/h4-7,14-17,23H,8-13,32H2,1-3H3/t17-,23+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to MC4 receptor				Bioorg Med Chem Lett 18: 1931-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.125 BindingDB Entry DOI: 10.7270/Q2WD409C
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50191011 ((R)-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-(trifluo...) Show SMILES CC(C)C[C@H](N)c1cc(ccc1N1CCN(CC1)C(=O)[C@H](C)Cc1ccc(Cl)cc1Cl)C(F)(F)F Show InChI InChI=1S/C26H32Cl2F3N3O/c1-16(2)12-23(32)21-14-19(26(29,30)31)5-7-24(21)33-8-10-34(11-9-33)25(35)17(3)13-18-4-6-20(27)15-22(18)28/h4-7,14-17,23H,8-13,32H2,1-3H3/t17-,23+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity at human MC4R				Bioorg Med Chem Lett 18: 1124-30 (2008) Article DOI: 10.1016/j.bmcl.2007.11.128 BindingDB Entry DOI: 10.7270/Q2GF0T7H
					More data for this Ligand-Target Pair