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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50235761'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM50235761
PNG
((2R,3R)-ethyl 2-(1-(2-((S)-1-amino-2-methylpropyl)...)
Show SMILES CCOC(=O)N1CC[C@@H]([C@@H]1C(=O)N1CCN(CC1)c1ccc(F)cc1[C@@H](N)C(C)C)c1ccc(Cl)cc1
Show InChI InChI=1S/C28H36ClFN4O3/c1-4-37-28(36)34-12-11-22(19-5-7-20(29)8-6-19)26(34)27(35)33-15-13-32(14-16-33)24-10-9-21(30)17-23(24)25(31)18(2)3/h5-10,17-18,22,25-26H,4,11-16,31H2,1-3H3/t22-,25+,26-/m1/s1
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Similars
Article
PubMed
 74n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Displacement of [125]NDPMSH from human MC4 receptor expressed in HEK293 cells

Bioorg Med Chem Lett 18: 1931-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.125
BindingDB Entry DOI: 10.7270/Q2WD409C
More data for this
Ligand-Target Pair