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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50266723'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Mus musculus)		BDBM50266723
PNG
(CHEMBL4087093)
Show SMILES CC(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N[C@H](Cc1ccc2ccccc2c1)C(N)=O |r|
Show InChI InChI=1S/C45H49IN8O5/c1-28(55)51-39(25-29-13-18-34(19-14-29)32-8-3-2-4-9-32)43(58)52-37(12-7-23-50-45(48)49)42(57)54-40(26-30-16-21-36(46)22-17-30)44(59)53-38(41(47)56)27-31-15-20-33-10-5-6-11-35(33)24-31/h2-6,8-11,13-22,24,37-40H,7,12,23,25-27H2,1H3,(H2,47,56)(H,51,55)(H,52,58)(H,53,59)(H,54,57)(H4,48,49,50)/t37-,38+,39-,40+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Agonist activity at mouse MC4R expressed in HEK293 cells assessed as induction of cAMP accumulation after 2 hrs by alpha screen assay

J Med Chem 60: 4342-4357 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00301
BindingDB Entry DOI: 10.7270/Q24170J1
More data for this
Ligand-Target Pair