Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50348564'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50348564 (CHEMBL1801122) Show SMILES Cc1cc2[C@H](CC3(CCN(CC3)C(=O)[C@@H]3CN(C[C@H]3c3ccc(F)cc3F)C(C)(C)C)c2cc1Cl)C(C)(C)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C40H48ClF2N3O2/c1-25-18-29-32(20-34(25)41)40(21-33(29)39(5,6)37(48)44-22-26-10-8-7-9-11-26)14-16-45(17-15-40)36(47)31-24-46(38(2,3)4)23-30(31)28-13-12-27(42)19-35(28)43/h7-13,18-20,30-31,33H,14-17,21-24H2,1-6H3,(H,44,48)/t30-,31+,33-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-NDP-R-MSH from human MC4R expressed in CHO cells after 1.5 hrs by scintillation counting				Bioorg Med Chem Lett 20: 4399-405 (2010) Article DOI: 10.1016/j.bmcl.2010.06.062 BindingDB Entry DOI: 10.7270/Q23F4Q07
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50348564 (CHEMBL1801122) Show SMILES Cc1cc2[C@H](CC3(CCN(CC3)C(=O)[C@@H]3CN(C[C@H]3c3ccc(F)cc3F)C(C)(C)C)c2cc1Cl)C(C)(C)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C40H48ClF2N3O2/c1-25-18-29-32(20-34(25)41)40(21-33(29)39(5,6)37(48)44-22-26-10-8-7-9-11-26)14-16-45(17-15-40)36(47)31-24-46(38(2,3)4)23-30(31)28-13-12-27(42)19-35(28)43/h7-13,18-20,30-31,33H,14-17,21-24H2,1-6H3,(H,44,48)/t30-,31+,33-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human MC4R expressed in CHO cells assessed as increase of alpha-MSH-stimulated cAMP release pretreated for 10 mins before alpha-M...				Bioorg Med Chem Lett 20: 4399-405 (2010) Article DOI: 10.1016/j.bmcl.2010.06.062 BindingDB Entry DOI: 10.7270/Q23F4Q07
					More data for this Ligand-Target Pair