Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50514456'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Mus musculus)	BDBM50514456 (CHEMBL4587214) Show SMILES [H][C@@]12CCCN1C(=O)[C@@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC2=O |r| Show InChI InChI=1S/C50H59N11O9/c1-30-43(63)59-39(25-33-17-9-4-10-18-33)49(69)61-22-12-20-41(61)50(70)60-21-11-19-40(60)48(68)58-37(26-34-28-52-29-53-34)47(67)56-35(23-31-13-5-2-6-14-31)45(65)55-36(24-32-15-7-3-8-16-32)46(66)57-38(27-42(51)62)44(64)54-30/h2-10,13-18,28-30,35-41H,11-12,19-27H2,1H3,(H2,51,62)(H,52,53)(H,54,64)(H,55,65)(H,56,67)(H,57,66)(H,58,68)(H,59,63)/t30-,35-,36-,37-,38-,39-,40-,41+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Displacement of [125I]-NDP-MSH from mouse melanocortin receptor 4 expressed in HEK293 cell mebranes incubated for 1 hr by automatic gamma counting me...				J Med Chem 63: 2194-2208 (2020) Article DOI: 10.1021/acs.jmedchem.9b00860 BindingDB Entry DOI: 10.7270/Q25142KG
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50514456 (CHEMBL4587214) Show SMILES [H][C@@]12CCCN1C(=O)[C@@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC2=O |r| Show InChI InChI=1S/C50H59N11O9/c1-30-43(63)59-39(25-33-17-9-4-10-18-33)49(69)61-22-12-20-41(61)50(70)60-21-11-19-40(60)48(68)58-37(26-34-28-52-29-53-34)47(67)56-35(23-31-13-5-2-6-14-31)45(65)55-36(24-32-15-7-3-8-16-32)46(66)57-38(27-42(51)62)44(64)54-30/h2-10,13-18,28-30,35-41H,11-12,19-27H2,1H3,(H2,51,62)(H,52,53)(H,54,64)(H,55,65)(H,56,67)(H,57,66)(H,58,68)(H,59,63)/t30-,35-,36-,37-,38-,39-,40-,41+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Displacement of [125I]-NDP-MSH from human melanocortin receptor 4 expressed in HEK293 cell mebranes incubated for 1 hr by automatic gamma counting me...				J Med Chem 63: 2194-2208 (2020) Article DOI: 10.1021/acs.jmedchem.9b00860 BindingDB Entry DOI: 10.7270/Q25142KG
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Mus musculus)	BDBM50514456 (CHEMBL4587214) Show SMILES [H][C@@]12CCCN1C(=O)[C@@]1([H])CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC2=O |r| Show InChI InChI=1S/C50H59N11O9/c1-30-43(63)59-39(25-33-17-9-4-10-18-33)49(69)61-22-12-20-41(61)50(70)60-21-11-19-40(60)48(68)58-37(26-34-28-52-29-53-34)47(67)56-35(23-31-13-5-2-6-14-31)45(65)55-36(24-32-15-7-3-8-16-32)46(66)57-38(27-42(51)62)44(64)54-30/h2-10,13-18,28-30,35-41H,11-12,19-27H2,1H3,(H2,51,62)(H,52,53)(H,54,64)(H,55,65)(H,56,67)(H,57,66)(H,58,68)(H,59,63)/t30-,35-,36-,37-,38-,39-,40-,41+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP ...				J Med Chem 63: 2194-2208 (2020) Article DOI: 10.1021/acs.jmedchem.9b00860 BindingDB Entry DOI: 10.7270/Q25142KG
					More data for this Ligand-Target Pair