Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Membrane primary amine oxidase (Rattus norvegicus (Rat)) | BDBM129007![]() (US8802679, 263) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | 25 |
Astellas Pharma Inc. US Patent | Assay Description A rat VAP-enzyme 1 (SSAO) activity was measured by a radiochemistry-enzymatic assay using 14C-benzylamine as an artificial substrate. An enzyme suspe... | US Patent US8802679 (2014) BindingDB Entry DOI: 10.7270/Q2M61HZD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Membrane primary amine oxidase (Rattus norvegicus (Rat)) | BDBM129007![]() (US8802679, 263) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Drug Discovery Research, Astellas Pharma Inc., 21 Miyukigaoka, Tsukuba, Ibaraki 305-8585, Japan. Electronic address: susumu.yamaki@astellas.com. Curated by ChEMBL | Assay Description Inhibition of rat VAP-1 expressed in CHO cells using 14C-benzylamine as substrate preincubated for 20 mins followed by substrate addition measured af... | Bioorg Med Chem 25: 4110-4122 (2017) Article DOI: 10.1016/j.bmc.2017.05.059 BindingDB Entry DOI: 10.7270/Q21Z46W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Membrane primary amine oxidase (Homo sapiens (Human)) | BDBM129007![]() (US8802679, 263) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Drug Discovery Research, Astellas Pharma Inc., 21 Miyukigaoka, Tsukuba, Ibaraki 305-8585, Japan. Electronic address: susumu.yamaki@astellas.com. Curated by ChEMBL | Assay Description Inhibition of human VAP-1 expressed in CHO cells using 14C-benzylamine as substrate preincubated for 20 mins followed by substrate addition measured ... | Bioorg Med Chem 25: 4110-4122 (2017) Article DOI: 10.1016/j.bmc.2017.05.059 BindingDB Entry DOI: 10.7270/Q21Z46W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Membrane primary amine oxidase (Homo sapiens (Human)) | BDBM129007![]() (US8802679, 263) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | 25 |
Astellas Pharma Inc. US Patent | Assay Description A human VAP-1 enzyme (SSAO) activity was measured by a radiochemistry-enzymatic assay using 14C-benzylamine as an artificial substrate. An enzyme sus... | US Patent US8802679 (2014) BindingDB Entry DOI: 10.7270/Q2M61HZD | |||||||||||
More data for this Ligand-Target Pair |