Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Membrane primary amine oxidase' and Ligand = 'BDBM309488'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM309488 (US9603833, Example 110) Show SMILES CC(=O)N1CCN(CC1)c1ccc(CCc2ccc(OC(=O)NN)cc2)nc1 Show InChI InChI=1S/C20H25N5O3/c1-15(26)24-10-12-25(13-11-24)18-7-6-17(22-14-18)5-2-16-3-8-19(9-4-16)28-20(27)23-21/h3-4,6-9,14H,2,5,10-13,21H2,1H3,(H,23,27)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
R-Tech Ueno, Ltd. US Patent					Assay Description The compounds of the present invention obtained in Production Examples were examined for the inhibitory effect on human and rat VAP-1 enzyme (SSAO) b...				US Patent US9603833 (2017) BindingDB Entry DOI: 10.7270/Q2W37ZCW
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM309488 (US9603833, Example 110) Show SMILES CC(=O)N1CCN(CC1)c1ccc(CCc2ccc(OC(=O)NN)cc2)nc1 Show InChI InChI=1S/C20H25N5O3/c1-15(26)24-10-12-25(13-11-24)18-7-6-17(22-14-18)5-2-16-3-8-19(9-4-16)28-20(27)23-21/h3-4,6-9,14H,2,5,10-13,21H2,1H3,(H,23,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
R-Tech Ueno, Ltd. US Patent					Assay Description The compounds of the present invention obtained in Production Examples were examined for the inhibitory effect on human and rat VAP-1 enzyme (SSAO) b...				US Patent US9603833 (2017) BindingDB Entry DOI: 10.7270/Q2W37ZCW
					More data for this Ligand-Target Pair