Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Membrane primary amine oxidase' and Ligand = 'BDBM309489'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM309489 (US9603833, Example 111) Show SMILES CC(=O)N1CCN(CC1)c1ccc(CCc2cccc(COC(=O)NN)c2)nc1 Show InChI InChI=1S/C21H27N5O3/c1-16(27)25-9-11-26(12-10-25)20-8-7-19(23-14-20)6-5-17-3-2-4-18(13-17)15-29-21(28)24-22/h2-4,7-8,13-14H,5-6,9-12,15,22H2,1H3,(H,24,28)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
R-Tech Ueno, Ltd. US Patent					Assay Description The compounds of the present invention obtained in Production Examples were examined for the inhibitory effect on human and rat VAP-1 enzyme (SSAO) b...				US Patent US9603833 (2017) BindingDB Entry DOI: 10.7270/Q2W37ZCW
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM309489 (US9603833, Example 111) Show SMILES CC(=O)N1CCN(CC1)c1ccc(CCc2cccc(COC(=O)NN)c2)nc1 Show InChI InChI=1S/C21H27N5O3/c1-16(27)25-9-11-26(12-10-25)20-8-7-19(23-14-20)6-5-17-3-2-4-18(13-17)15-29-21(28)24-22/h2-4,7-8,13-14H,5-6,9-12,15,22H2,1H3,(H,24,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
R-Tech Ueno, Ltd. US Patent					Assay Description The compounds of the present invention obtained in Production Examples were examined for the inhibitory effect on human and rat VAP-1 enzyme (SSAO) b...				US Patent US9603833 (2017) BindingDB Entry DOI: 10.7270/Q2W37ZCW
					More data for this Ligand-Target Pair