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Found 1 hit Enz. Inhib. hit(s) with Target = 'Membrane primary amine oxidase' and Ligand = 'BDBM50262737'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Membrane primary amine oxidase


(Homo sapiens (Human))		BDBM50262737
PNG
(CHEMBL4087881)
Show SMILES Cl.Cl.Cl.NC(=N)NC(=O)OCc1cccc(c1)N1CCN(CC1)c1ccncc1
Show InChI InChI=1S/C18H22N6O2/c19-17(20)22-18(25)26-13-14-2-1-3-16(12-14)24-10-8-23(9-11-24)15-4-6-21-7-5-15/h1-7,12H,8-11,13H2,(H4,19,20,22,25)
PDB
MMDB

KEGG

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 13n/an/an/an/an/an/a



Drug Discovery Research, Astellas Pharma Inc., 21 Miyukigaoka, Tsukuba, Ibaraki 305-8585, Japan. Electronic address: susumu.yamaki@astellas.com.

Curated by ChEMBL


Assay Description
Inhibition of human VAP-1 expressed in CHO cells preincubated for 20 mins followed by [14C]-benzylamine addition measured after 1 hr by scintillation...

Bioorg Med Chem 25: 6024-6038 (2017)


Article DOI: 10.1016/j.bmc.2017.09.036
BindingDB Entry DOI: 10.7270/Q2B27XR3
More data for this
Ligand-Target Pair