Found 2 hits Enz. Inhib. hit(s) with Target = 'Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase' and Ligand = 'BDBM50598835' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
(Homo sapiens (Human)) | BDBM50598835
(CHEMBL5169345)Show SMILES Cc1ccc(O)c(C)c1-n1c(N)c(C(N)=O)c2nc3cccc(-c4ccnn4C)c3nc12 |(2.67,-4.15,;2.96,-2.95,;4.44,-2.52,;4.8,-1.03,;3.69,.04,;3.98,1.24,;2.21,-.39,;1.32,.45,;1.85,-1.89,;.34,-2.21,;-.28,-3.62,;.33,-4.69,;-1.81,-3.46,;-2.84,-4.61,;-4.05,-4.35,;-2.46,-5.78,;-2.13,-1.95,;-3.47,-1.18,;-3.47,.36,;-4.8,1.13,;-4.8,2.67,;-3.47,3.44,;-2.13,2.67,;-.8,3.44,;.59,2.8,;1.62,3.94,;.85,5.27,;-.66,4.96,;-1.58,5.78,;-2.13,1.13,;-.8,.36,;-.8,-1.18,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | <3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00552 BindingDB Entry DOI: 10.7270/Q2028WKQ |
More data for this Ligand-Target Pair | |
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
(Homo sapiens (Human)) | BDBM50598835
(CHEMBL5169345)Show SMILES Cc1ccc(O)c(C)c1-n1c(N)c(C(N)=O)c2nc3cccc(-c4ccnn4C)c3nc12 |(2.67,-4.15,;2.96,-2.95,;4.44,-2.52,;4.8,-1.03,;3.69,.04,;3.98,1.24,;2.21,-.39,;1.32,.45,;1.85,-1.89,;.34,-2.21,;-.28,-3.62,;.33,-4.69,;-1.81,-3.46,;-2.84,-4.61,;-4.05,-4.35,;-2.46,-5.78,;-2.13,-1.95,;-3.47,-1.18,;-3.47,.36,;-4.8,1.13,;-4.8,2.67,;-3.47,3.44,;-2.13,2.67,;-.8,3.44,;.59,2.8,;1.62,3.94,;.85,5.27,;-.66,4.96,;-1.58,5.78,;-2.13,1.13,;-.8,.36,;-.8,-1.18,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00552 BindingDB Entry DOI: 10.7270/Q2028WKQ |
More data for this Ligand-Target Pair | |