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Found 1 hit Enz. Inhib. hit(s) with Target = 'Menin' and Ligand = 'BDBM50496353'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Menin


(Homo sapiens (Human))		BDBM50496353
PNG
(CHEMBL3126183)
Show SMILES CC(C)C(O)(C1CCN(CCCOc2ccc(cc2)C#N)CC1)c1ccccc1
Show InChI InChI=1S/C25H32N2O2/c1-20(2)25(28,22-7-4-3-5-8-22)23-13-16-27(17-14-23)15-6-18-29-24-11-9-21(19-26)10-12-24/h3-5,7-12,20,23,28H,6,13-18H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.10E+3n/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Inhibition of human His-tagged menin-biotinylated MLL (4 to 15) interaction after 1 hr by HTRF assay

J Med Chem 57: 1543-56 (2014)


Article DOI: 10.1021/jm401868d
BindingDB Entry DOI: 10.7270/Q2XS5ZCB
More data for this
Ligand-Target Pair