BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Ligand = 'BDBM50079183'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Metabotropic glutamate receptor 1 (RAT)	BDBM50079183 ((2S)-amino(3,5-dihydroxyphenyl)ethanoic acid \| (S)...) Show SMILES N[C@H](C(O)=O)c1cc(O)cc(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Parc Club Orsay Universit£ Curated by ChEMBL					Assay Description Binding affinity at Metabotropic glutamate receptor 1				J Med Chem 45: 3171-83 (2002) BindingDB Entry DOI: 10.7270/Q2B27W18
Parc Club Orsay Universit£ Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50079183 ((2S)-amino(3,5-dihydroxyphenyl)ethanoic acid \| (S)...) Show SMILES N[C@H](C(O)=O)c1cc(O)cc(O)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP K_i Database									Annu Rev Pharmacol Toxicol 37: 205-37 (1997) Article DOI: 10.1146/annurev.pharmtox.37.1.205 BindingDB Entry DOI: 10.7270/Q2M043ZH
Emory University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50079183 ((2S)-amino(3,5-dihydroxyphenyl)ethanoic acid \| (S)...) Show SMILES N[C@H](C(O)=O)c1cc(O)cc(O)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PubMed	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Agonist potency against cloned human metabotropic glutamate receptor 1				J Med Chem 43: 2609-45 (2000) BindingDB Entry DOI: 10.7270/Q2DZ090Q
The Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50079183 ((2S)-amino(3,5-dihydroxyphenyl)ethanoic acid \| (S)...) Show SMILES N[C@H](C(O)=O)c1cc(O)cc(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development, Beerse Curated by PDSP K_i Database									Mol Pharmacol 63: 1082-93 (2003) Article DOI: 10.1124/mol.63.5.1082 BindingDB Entry DOI: 10.7270/Q2BV7F62
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50079183 ((2S)-amino(3,5-dihydroxyphenyl)ethanoic acid \| (S)...) Show SMILES N[C@H](C(O)=O)c1cc(O)cc(O)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a
Universit¿a di Perugia Curated by ChEMBL					Assay Description Compound was tested for its agonist activity against Ser165 and Thr188 (Metabotropic glutamate receptor 1) receptor.				J Med Chem 42: 5390-401 (2000) BindingDB Entry DOI: 10.7270/Q2ZG6RGS
Universit¿a di Perugia Curated by ChEMBL					More data for this Ligand-Target Pair