BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Ligand = 'BDBM50109653'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 1


(RAT)		BDBM50109653
PNG
(2-Amino-3-[3-hydroxy-4-(4-hydroxy-phenyl)-isoxazol...)
Show SMILES N[C@@H](Cc1o[nH]c(=O)c1-c1ccc(O)cc1)C(O)=O
Show InChI InChI=1S/C12H12N2O5/c13-8(12(17)18)5-9-10(11(16)14-19-9)6-1-3-7(15)4-2-6/h1-4,8,15H,5,13H2,(H,14,16)(H,17,18)/t8-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 7.10E+4n/an/an/an/an/an/an/an/a



The Royal Danish School of Pharmacy

Curated by ChEMBL


Assay Description
The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 1 using established second messenger assay systems.

J Med Chem 45: 988-91 (2002)


BindingDB Entry DOI: 10.7270/Q2M32V27
More data for this
Ligand-Target Pair