Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Ligand = 'BDBM50177086'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (RAT)	BDBM50177086 (3-(4-Ethyl-phenyl)-9-methylamino-3H-pyrido[3',2':4...) Show SMILES CCc1ccc(cc1)-n1cnc2c(sc3nccc(NC)c23)c1=O Show InChI InChI=1S/C18H16N4OS/c1-3-11-4-6-12(7-5-11)22-10-21-15-14-13(19-2)8-9-20-17(14)24-16(15)18(22)23/h4-10H,3H2,1-2H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Biocampus Curated by ChEMBL					Assay Description Inhibition of rat mGluR1				Eur J Med Chem 43: 1025-34 (2008) Article DOI: 10.1016/j.ejmech.2007.06.024 BindingDB Entry DOI: 10.7270/Q2V987VM
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50177086 (3-(4-Ethyl-phenyl)-9-methylamino-3H-pyrido[3',2':4...) Show SMILES CCc1ccc(cc1)-n1cnc2c(sc3nccc(NC)c23)c1=O Show InChI InChI=1S/C18H16N4OS/c1-3-11-4-6-12(7-5-11)22-10-21-15-14-13(19-2)8-9-20-17(14)24-16(15)18(22)23/h4-10H,3H2,1-2H3,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human mGluR1 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilization				J Med Chem 48: 7374-88 (2005) Article DOI: 10.1021/jm0504407 BindingDB Entry DOI: 10.7270/Q27P8XX0
					More data for this Ligand-Target Pair