Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Ligand = 'BDBM50177099'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (RAT)	BDBM50177099 (9-Dimethylamino-3-(3-methyl-cyclohexyl)-3H-pyrido[...) Show SMILES CC1CCCC(C1)n1cnc2c(sc3nccc(N(C)C)c23)c1=O Show InChI InChI=1S/C18H22N4OS/c1-11-5-4-6-12(9-11)22-10-20-15-14-13(21(2)3)7-8-19-17(14)24-16(15)18(22)23/h7-8,10-12H,4-6,9H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	482	n/a	n/a	n/a	n/a	n/a	n/a
Biocampus Curated by ChEMBL					Assay Description Inhibition of rat mGluR1				Eur J Med Chem 43: 1025-34 (2008) Article DOI: 10.1016/j.ejmech.2007.06.024 BindingDB Entry DOI: 10.7270/Q2V987VM
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50177099 (9-Dimethylamino-3-(3-methyl-cyclohexyl)-3H-pyrido[...) Show SMILES CC1CCCC(C1)n1cnc2c(sc3nccc(N(C)C)c23)c1=O Show InChI InChI=1S/C18H22N4OS/c1-11-5-4-6-12(9-11)22-10-20-15-14-13(21(2)3)7-8-19-17(14)24-16(15)18(22)23/h7-8,10-12H,4-6,9H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	482	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human mGluR1 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilization				J Med Chem 48: 7374-88 (2005) Article DOI: 10.1021/jm0504407 BindingDB Entry DOI: 10.7270/Q27P8XX0
					More data for this Ligand-Target Pair