Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM252689'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM252689 (US9458176, 86) Show SMILES C[C@@H]1Cn2c(CCO1)c(nc2-c1ccc(OC(F)(F)F)cc1)-c1cc(C)nc(CF)c1 |r| Show InChI InChI=1S/C22H21F4N3O2/c1-13-9-16(10-17(11-23)27-13)20-19-7-8-30-14(2)12-29(19)21(28-20)15-3-5-18(6-4-15)31-22(24,25)26/h3-6,9-10,14H,7-8,11-12H2,1-2H3/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	25
Eisai R&D Management Co., Ltd. US Patent					Assay Description The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...				US Patent US9458176 (2016) BindingDB Entry DOI: 10.7270/Q2PK0F3D
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