Compile Data Set for Download or QSAR

Found 8 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM393732'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM393732 (US10597367, Example 28 | US9969726, Example 22 | U...) Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...				J Med Chem 52: 1935-42 (2009) BindingDB Entry DOI: 10.7270/Q2RX9FDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM393732 (US10597367, Example 28 | US9969726, Example 22 | U...) Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...				J Med Chem 52: 1935-42 (2009) BindingDB Entry DOI: 10.7270/Q2RX9FDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM393732 (US10597367, Example 28 | US9969726, Example 22 | U...) Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	420	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...				J Med Chem 52: 1935-42 (2009) BindingDB Entry DOI: 10.7270/Q2RX9FDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM393732 (US10597367, Example 28 | US9969726, Example 22 | U...) Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...				US Patent US10597367 (2020) BindingDB Entry DOI: 10.7270/Q2GB272Z
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM393732 (US10597367, Example 28 | US9969726, Example 22 | U...) Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...				US Patent US10597367 (2020) BindingDB Entry DOI: 10.7270/Q2GB272Z
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM393732 (US10597367, Example 28 | US9969726, Example 22 | U...) Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...				US Patent US10597367 (2020) BindingDB Entry DOI: 10.7270/Q2GB272Z
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM393732 (US10597367, Example 28 | US9969726, Example 22 | U...) Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	420	n/a	n/a	n/a	n/a
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE US Patent					Assay Description Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...				US Patent US10597367 (2020) BindingDB Entry DOI: 10.7270/Q2GB272Z
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM393732 (US10597367, Example 28 | US9969726, Example 22 | U...) Show SMILES c1sc(nc1-c1cccc(c1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C21H15NS/c1-3-8-16(9-4-1)18-12-7-13-19(14-18)20-15-23-21(22-20)17-10-5-2-6-11-17/h1-15H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Universita degli Studi di Roma La Sapienza					Assay Description Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...				J Med Chem 52: 1935-42 (2009) BindingDB Entry DOI: 10.7270/Q2RX9FDX
					More data for this Ligand-Target Pair