Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50343309'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50343309 (1-Methyl-2-((4-(4-(trifluoromethyl)phenyl)piperidi...) Show SMILES Cn1c(CN2CCC(CC2)c2ccc(cc2)C(F)(F)F)nc2cnccc12 Show InChI InChI=1S/C20H21F3N4/c1-26-18-6-9-24-12-17(18)25-19(26)13-27-10-7-15(8-11-27)14-2-4-16(5-3-14)20(21,22)23/h2-6,9,12,15H,7-8,10-11,13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	168	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced int...				J Med Chem 54: 1724-39 (2011) Article DOI: 10.1021/jm101414h BindingDB Entry DOI: 10.7270/Q2222V3C
					More data for this Ligand-Target Pair