Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 3' and Ligand = 'BDBM50017211'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017211 (CHEMBL3287695 | US10099993, Compound 44) Show SMILES COc1cc(ccc1OCCCCOc1ccc(C(=O)CC(C)C)c(O)c1C)C(O)=O Show InChI InChI=1S/C24H30O7/c1-15(2)13-19(25)18-8-10-20(16(3)23(18)26)30-11-5-6-12-31-21-9-7-17(24(27)28)14-22(21)29-4/h7-10,14-15,26H,5-6,11-13H2,1-4H3,(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.77E+3	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR3 receptor expressed in TREx293 cells by calcium mobilization assay				J Med Chem 57: 4154-72 (2014) Article DOI: 10.1021/jm5000563 BindingDB Entry DOI: 10.7270/Q2GH9KH9
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50017211 (CHEMBL3287695 | US10099993, Compound 44) Show SMILES COc1cc(ccc1OCCCCOc1ccc(C(=O)CC(C)C)c(O)c1C)C(O)=O Show InChI InChI=1S/C24H30O7/c1-15(2)13-19(25)18-8-10-20(16(3)23(18)26)30-11-5-6-12-31-21-9-7-17(24(27)28)14-22(21)29-4/h7-10,14-15,26H,5-6,11-13H2,1-4H3,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	614	n/a	n/a	n/a	n/a
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE US Patent									US Patent US10099993 (2018) BindingDB Entry DOI: 10.7270/Q2Z89FFP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017211 (CHEMBL3287695 | US10099993, Compound 44) Show SMILES COc1cc(ccc1OCCCCOc1ccc(C(=O)CC(C)C)c(O)c1C)C(O)=O Show InChI InChI=1S/C24H30O7/c1-15(2)13-19(25)18-8-10-20(16(3)23(18)26)30-11-5-6-12-31-21-9-7-17(24(27)28)14-22(21)29-4/h7-10,14-15,26H,5-6,11-13H2,1-4H3,(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	614	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR3 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated...				J Med Chem 57: 4154-72 (2014) Article DOI: 10.1021/jm5000563 BindingDB Entry DOI: 10.7270/Q2GH9KH9
					More data for this Ligand-Target Pair