Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 3' and Ligand = 'BDBM50017246'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50017246 (CHEMBL3287687 | US10099993, Compound 36) Show SMILES CC(C)CC(=O)c1ccc(OCCCCOc2ccc(F)c(c2)C(O)=O)c(C)c1O Show InChI InChI=1S/C23H27FO6/c1-14(2)12-20(25)17-7-9-21(15(3)22(17)26)30-11-5-4-10-29-16-6-8-19(24)18(13-16)23(27)28/h6-9,13-14,26H,4-5,10-12H2,1-3H3,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	920	n/a	n/a	n/a	n/a
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE US Patent									US Patent US10099993 (2018) BindingDB Entry DOI: 10.7270/Q2Z89FFP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50017246 (CHEMBL3287687 | US10099993, Compound 36) Show SMILES CC(C)CC(=O)c1ccc(OCCCCOc2ccc(F)c(c2)C(O)=O)c(C)c1O Show InChI InChI=1S/C23H27FO6/c1-14(2)12-20(25)17-7-9-21(15(3)22(17)26)30-11-5-4-10-29-16-6-8-19(24)18(13-16)23(27)28/h6-9,13-14,26H,4-5,10-12H2,1-3H3,(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	920	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGluR3 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated...				J Med Chem 57: 4154-72 (2014) Article DOI: 10.1021/jm5000563 BindingDB Entry DOI: 10.7270/Q2GH9KH9
					More data for this Ligand-Target Pair