Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 4' and Ligand = 'BDBM368512'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM368512 (1-(1-methyl-1H-pyrazol- 5-yl)-N-(1H-pyrazolo [4,3-...) Show SMILES Cn1nccc1-c1nccc2cc(Nc3n[nH]c4cccnc34)ccc12 Show InChI InChI=1S/C19H15N7/c1-26-16(7-10-22-26)17-14-5-4-13(11-12(14)6-9-21-17)23-19-18-15(24-25-19)3-2-8-20-18/h2-11H,1H3,(H2,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human urine urokinase using L-PyroGlu-Gly-Arg-pNA.HCl substrate at 5 uM				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM368512 (1-(1-methyl-1H-pyrazol- 5-yl)-N-(1H-pyrazolo [4,3-...) Show SMILES Cn1nccc1-c1nccc2cc(Nc3n[nH]c4cccnc34)ccc12 Show InChI InChI=1S/C19H15N7/c1-26-16(7-10-22-26)17-14-5-4-13(11-12(14)6-9-21-17)23-19-18-15(24-25-19)3-2-8-20-18/h2-11H,1H3,(H2,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
Universita di Napoli					Assay Description The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...				J Med Chem 51: 1764-70 (2008) BindingDB Entry DOI: 10.7270/Q2X63Q8G
					More data for this Ligand-Target Pair