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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 4' and Ligand = 'BDBM50038038'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50038038
PNG
((S)-2-Amino-4-(3,5-dioxo-[1,2,4]oxadiazolidin-2-yl...)
Show SMILES N[C@@H](CCn1oc(=O)[nH]c1=O)C(O)=O
Show InChI InChI=1S/C6H9N3O5/c7-3(4(10)11)1-2-9-5(12)8-6(13)14-9/h3H,1-2,7H2,(H,10,11)(H,8,12,13)/t3-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
>1.00E+6n/an/an/an/an/an/an/an/a



The Royal Danish School of Pharmacy

Curated by ChEMBL


Assay Description
Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)


J Med Chem 43: 2609-45 (2000)


BindingDB Entry DOI: 10.7270/Q2DZ090Q
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4


(Rattus norvegicus (Rat))
BDBM50038038
PNG
((S)-2-Amino-4-(3,5-dioxo-[1,2,4]oxadiazolidin-2-yl...)
Show SMILES N[C@@H](CCn1oc(=O)[nH]c1=O)C(O)=O
Show InChI InChI=1S/C6H9N3O5/c7-3(4(10)11)1-2-9-5(12)8-6(13)14-9/h3H,1-2,7H2,(H,10,11)(H,8,12,13)/t3-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



Universit£ Ren£ Descartes-Paris V

Curated by ChEMBL


Assay Description
Stimulation of [3H]phosphatidylinositol accumulation by rat Metabotropic glutamate receptor 4 co-expressed with Gqi9 protein in HEK 293 cells; Inacti...


J Med Chem 48: 2534-47 (2005)


Article DOI: 10.1021/jm049092j
BindingDB Entry DOI: 10.7270/Q23X87FM
More data for this
Ligand-Target Pair