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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 4' and Ligand = 'BDBM50462740'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 4


(Homo sapiens (Human))		BDBM50462740
PNG
(CHEMBL4244458)
Show SMILES CN1CCC(CC1)Oc1nn(C)c2cc(Nc3n[nH]c4cccnc34)ccc12
Show InChI InChI=1S/C20H23N7O/c1-26-10-7-14(8-11-26)28-20-15-6-5-13(12-17(15)27(2)25-20)22-19-18-16(23-24-19)4-3-9-21-18/h3-6,9,12,14H,7-8,10-11H2,1-2H3,(H2,22,23,24)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.88E+3n/an/an/an/a



Vanderbilt University

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human mGluR4 expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium flux prein...

Bioorg Med Chem Lett 28: 2641-2646 (2018)


Article DOI: 10.1016/j.bmcl.2018.06.034
BindingDB Entry DOI: 10.7270/Q2DR2Z5H
More data for this
Ligand-Target Pair