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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 4' and Ligand = 'BDBM50462774'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 4


(Homo sapiens (Human))		BDBM50462774
PNG
(CHEMBL4248576)
Show SMILES Cn1nc(C(=O)N2CCC(F)(F)CC2)c2ccc(Nc3n[nH]c4cccnc34)cc12
Show InChI InChI=1S/C20H19F2N7O/c1-28-15-11-12(24-18-17-14(25-26-18)3-2-8-23-17)4-5-13(15)16(27-28)19(30)29-9-6-20(21,22)7-10-29/h2-5,8,11H,6-7,9-10H2,1H3,(H2,24,25,26)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 498n/an/an/an/a



Vanderbilt University

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human mGluR4 expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium flux prein...

Bioorg Med Chem Lett 28: 2641-2646 (2018)


Article DOI: 10.1016/j.bmcl.2018.06.034
BindingDB Entry DOI: 10.7270/Q2DR2Z5H
More data for this
Ligand-Target Pair