Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM107245'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM107245 (US8598345, Table 1-31) Show SMILES FC(F)(F)c1csc(NC(=O)c2cc(Oc3cccnc3)ccn2)n1 Show InChI InChI=1S/C15H9F3N4O2S/c16-15(17,18)12-8-25-14(21-12)22-13(23)11-6-9(3-5-20-11)24-10-2-1-4-19-7-10/h1-8H,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University US Patent					Assay Description mGluR5 activity was determined in a cell-based assay.				US Patent US8598345 (2013) BindingDB Entry DOI: 10.7270/Q2RR1WX8
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