Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM222818'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM222818 (US11059766, WO2011128279 Ex. 109 | US9315498, 109) Show SMILES CN1[C@H]2CCC[C@H]2N(C1=O)c1ccc(cn1)C#Cc1cccc(F)c1 |r| Show InChI InChI=1S/C20H18FN3O/c1-23-17-6-3-7-18(17)24(20(23)25)19-11-10-15(13-22-19)9-8-14-4-2-5-16(21)12-14/h2,4-5,10-13,17-18H,3,6-7H2,1H3/t17-,18+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For binding experiments, cDNA encoding human mGlu5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger and...				Citation and Details BindingDB Entry DOI: 10.7270/Q23X89SX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM222818 (US11059766, WO2011128279 Ex. 109 | US9315498, 109) Show SMILES CN1[C@H]2CCC[C@H]2N(C1=O)c1ccc(cn1)C#Cc1cccc(F)c1 |r| Show InChI InChI=1S/C20H18FN3O/c1-23-17-6-3-7-18(17)24(20(23)25)19-11-10-15(13-22-19)9-8-14-4-2-5-16(21)12-14/h2,4-5,10-13,17-18H,3,6-7H2,1H3/t17-,18+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
TBA					Assay Description For binding experiments, cDNA encoding human mGlu5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger and...				Citation and Details BindingDB Entry DOI: 10.7270/Q23X89SX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM222818 (US11059766, WO2011128279 Ex. 109 | US9315498, 109) Show SMILES CN1[C@H]2CCC[C@H]2N(C1=O)c1ccc(cn1)C#Cc1cccc(F)c1 |r| Show InChI InChI=1S/C20H18FN3O/c1-23-17-6-3-7-18(17)24(20(23)25)19-11-10-15(13-22-19)9-8-14-4-2-5-16(21)12-14/h2,4-5,10-13,17-18H,3,6-7H2,1H3/t17-,18+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
TBA					Assay Description A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...				Citation and Details BindingDB Entry DOI: 10.7270/Q23X89SX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM222818 (US11059766, WO2011128279 Ex. 109 | US9315498, 109) Show SMILES CN1[C@H]2CCC[C@H]2N(C1=O)c1ccc(cn1)C#Cc1cccc(F)c1 |r| Show InChI InChI=1S/C20H18FN3O/c1-23-17-6-3-7-18(17)24(20(23)25)19-11-10-15(13-22-19)9-8-14-4-2-5-16(21)12-14/h2,4-5,10-13,17-18H,3,6-7H2,1H3/t17-,18+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
TBA					Assay Description A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...				Citation and Details BindingDB Entry DOI: 10.7270/Q23X89SX
					More data for this Ligand-Target Pair