Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM292190'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM292190 (US10100057, Example 45 | US11046702, Example 45 | ...) Show SMILES Fc1cccc(OCc2cn3cc(cnc3n2)-c2ccncc2Cl)c1 Show InChI InChI=1S/C18H12ClFN4O/c19-17-8-21-5-4-16(17)12-7-22-18-23-14(10-24(18)9-12)11-25-15-3-1-2-13(20)6-15/h1-10H,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	25
SK BIOPHARMACEUTICALS CO., LTD. US Patent					Assay Description Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...				US Patent US10100057 (2018) BindingDB Entry DOI: 10.7270/Q2028TKW
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM292190 (US10100057, Example 45 | US11046702, Example 45 | ...) Show SMILES Fc1cccc(OCc2cn3cc(cnc3n2)-c2ccncc2Cl)c1 Show InChI InChI=1S/C18H12ClFN4O/c19-17-8-21-5-4-16(17)12-7-22-18-23-14(10-24(18)9-12)11-25-15-3-1-2-13(20)6-15/h1-10H,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
TBA					Assay Description Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...				Citation and Details BindingDB Entry DOI: 10.7270/Q2SQ93HC
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM292190 (US10100057, Example 45 | US11046702, Example 45 | ...) Show SMILES Fc1cccc(OCc2cn3cc(cnc3n2)-c2ccncc2Cl)c1 Show InChI InChI=1S/C18H12ClFN4O/c19-17-8-21-5-4-16(17)12-7-22-18-23-14(10-24(18)9-12)11-25-15-3-1-2-13(20)6-15/h1-10H,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
SK BIOPHARMACEUTICALS CO., LTD. US Patent					Assay Description Ca2+ (calcium) influx assay is an experiment for measuring the activity of a positive allosteric modulator of mGluR5 receptor in which human mGluR5 r...				US Patent US9745310 (2017) BindingDB Entry DOI: 10.7270/Q24T6MG4
					More data for this Ligand-Target Pair