Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50050071'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50050071 (CHEMBL3317729) Show SMILES Clc1ccc(cc1)-c1c(sc2ncccc12)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H11Cl2NO2S2/c20-13-5-3-12(4-6-13)17-16-2-1-11-22-18(16)25-19(17)26(23,24)15-9-7-14(21)8-10-15/h1-11H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptor				Bioorg Med Chem Lett 25: 1724-9 (2015) Article DOI: 10.1016/j.bmcl.2015.02.073 BindingDB Entry DOI: 10.7270/Q2JS9S47
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50050071 (CHEMBL3317729) Show SMILES Clc1ccc(cc1)-c1c(sc2ncccc12)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H11Cl2NO2S2/c20-13-5-3-12(4-6-13)17-16-2-1-11-22-18(16)25-19(17)26(23,24)15-9-7-14(21)8-10-15/h1-11H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]-M-MPEP from mGluR5 in rat cerebrocortical membrane preparation				Bioorg Med Chem Lett 24: 3845-9 (2014) Article DOI: 10.1016/j.bmcl.2014.06.057 BindingDB Entry DOI: 10.7270/Q2HH6MR1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50050071 (CHEMBL3317729) Show SMILES Clc1ccc(cc1)-c1c(sc2ncccc12)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H11Cl2NO2S2/c20-13-5-3-12(4-6-13)17-16-2-1-11-22-18(16)25-19(17)26(23,24)15-9-7-14(21)8-10-15/h1-11H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Negative allosteric modulation of mGlu5 receptor in primary E17 rat embryo neuron assessed as ca2+ level by fluo-4/AM assay				Bioorg Med Chem Lett 25: 1724-9 (2015) Article DOI: 10.1016/j.bmcl.2015.02.073 BindingDB Entry DOI: 10.7270/Q2JS9S47
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50050071 (CHEMBL3317729) Show SMILES Clc1ccc(cc1)-c1c(sc2ncccc12)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H11Cl2NO2S2/c20-13-5-3-12(4-6-13)17-16-2-1-11-22-18(16)25-19(17)26(23,24)15-9-7-14(21)8-10-15/h1-11H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Inhibition of mGluR5 in rat embryo neuronal culture assessed as calcium level by Fluo-4/AM dye based fluorometry				Bioorg Med Chem Lett 24: 3845-9 (2014) Article DOI: 10.1016/j.bmcl.2014.06.057 BindingDB Entry DOI: 10.7270/Q2HH6MR1
					More data for this Ligand-Target Pair